> Home DNA Test Review Comparison

Use this ratings chart to review and compare the different genetic variations associated with Lung Cancer and tested by home DNA testing providers. These findings are the result of an independent comparison of personal genomic company public information.

Lung Cancer

Genetic Variation			Companies				References*
Chromosome or Locus	Gene	SNP	deCODEme	Navigenics	23andMe	Gene Essence	deCODEme	Navigenics	23andMe
15	CHRNA3 / LOC123688	rs8034191						1	1,2,3,4,5,7,8,9
15	CHRNA3/A5/B4	rs1051730					7
		rs1056836
		rs17483721
		rs17483929
		rs17487223
		rs1800566
5	TERT	rs401681					6
		rs951266

*Research references cited by companies:

1. Amos, CI et al. Nat Genet. 2008 May;40(5):616-22. Epub 2008 Apr 2.
2. Ho et al (2005) Toxicol Appl Pharmacol 205(2):133-48.
3. Hung et al (2008) Nature 452(7187):633-7.
4. Lam et al (2007) Cancer Res 67(10):4638-47.
5. Minna (2003) J Clin Invest 111(1):31-3.
6. Rafnar, T et al. Nat Genet. 2009 Feb;41(2):221-7. Epub 2009 Jan 18.
7. Thorgeirsson, TE et al. Nature. 2008 Apr 3;452(7187):638-42.
8. trombino et al (2004) Cancer Res 64(1):135-45.
9. Zhang et al. (2007) Clin Cancer Res 13(16):4686-94.

Sources:

http://demo.decodeme.com/health-watch/details/LCA

https://www.23andme.com/you/journal/lungcancer/techreport/

http://www.navigenics.com/demo/for_scientists/d/lung_cancer/

http://www.geneessence.com/bmsa_0000/bmsa0000/lc.html