> Cancer Genetics

Researchers have found that the gene GPC5 is more common in non-smokers who have lung cancer than in non-smokers without the disease. Non-smokers rarely get lung cancer, so the study suffers the problem of having a small sample size. Nevertheless, researchers believe this is a good starting point in understanding and treating the disease.

Scientists at the Johns Hopkins Kimmel Cancer Center have used genetic data from the whole genome sequencing of cancer patients to develop individualized blood tests they believe may help physicians tailor patients' treatments. The genome-based blood tests can be used to monitor tumor levels after therapy and help determine cancer recurrence.

This article deals with information on prostate cancer cells. There was a recent study done that shows evidence that the caner is more likely to spread to other parts of the body if a specific gene quits functioning normally. This study was done by researchers at UT

Scientists exploring inflammatory disease treatment have discovered potential applications of a long-used Chinese medical treatment to control inflammation. The treatment uses a plant derivative which specifically targets protein HSP90, a critical component for cells undergoing inflammation. By removing this protein, the cancer cell cannot stabilize and is killed.

Article about study reveals that the protein MRG15, which previously had been known to affect cell growth and aging, also directs the gene-splicing machinery. This finding thus has potential implications for therapies to treat both cancer and aging, a Texas researcher said.

The most common type of lung cancer is adenocarcinoma. Often adenocarcinoma's cases are attributed to a mutation in a gene for the epidermal growth factor receptor (EGFR).Lung cancer with changes in EGFR is initially treatable with a family of chemotherapeutic agents called tyrosine kinase inhibitors (TKIs). Scientists now describe a mouse model of lung cancer that develops resistance to TKI drugs in at least some of the same ways that humans do.

This article deals with information on prostate cancer cells. There was a recent study done that shows evidence that the caner is more likely to spread to other parts of the body if a specific gene quits functioning normally. This study was done by researchers at UT

St Jude Hospital and Washington University join forces to look at the cancerous and normal cells of 600 pediatric patients in search of genetic markers. These markers may open the door to new and more effective treatment options.

A new DNA test for the virus that causes cervical cancer does so much better than current methods that some gynecologists hope it will eventually replace the Pap smear in wealthy countries and cruder tests in poor ones.

Tailoring cancer therapies to fit a person's genetic makeup could spare thousands of patients from harmful side effects and save millions of dollars a year, a study shows.

Most hereditary neuroblastomas in children, as well as many sporadic cases, are attributable to mutations in a known cancer-associated gene, researchers here said.

People who have two identical copies of certain genes -- one inherited from the mother and one from the father -- seem to be at greater risk of developing a number of common types of cancer, research shows.

Even though most U.S. medical groups are opposed, many people support genetic testing of children for mutations that predispose them to developing breast and/or ovarian cancer later in life, a new study says.

A new blood test that looks at five genetic variants could one day predict the risk of developing prostate cancer, a new study says.

Scientists have uncovered at least 10 new genetic variations associated with an increased risk for prostate cancer.