prnewswire.com | Submitted by AccessDNATeam, 04.26.10
Pediatric researchers have found that the interplay of genes involved in diabetes and inflammatory bowel disease is more complex than previously thought. Both type 1 diabetes and Crohn's disease are autoimmune diseases. Autoimmune diseases often have some genes in common, but these two disorders seem to be closely related. Certain genes appear to raise the risk of type 1 diabetes, while lowering the risk for Crohn's.
vancouversun.com | Submitted by Jordanna, 03.05.10
A promising new study reveals a gene mutation that may cause neonatal diabetes. A mutation in the RFX6 gene causes a rare syndrome of neonatal diabetes involving complete absence of the islets. Researchers say that finding a way to transform these cells promises a real solution for diabetes.
diabetes-stroke.com | Submitted by smboy5, 01.20.10
Can a gene providing health blessing or a curse disease? Apparently it is very possible depending on the genetic inheritance of the father or mother. The team of researchers from Iceland joined in Iceland’s Decode Genetics Inc. discovered the gene mutation in the five diseases that affect only if inherited from a particular parent.
A new gene associated with diabetes can protect a person from the disease, if inherited from the mother, but increases the risk if inherited from the father. Three other genes diabetes varied effect though not too dependent on the origin of their parents genes.
google.com | Submitted by smboy5, 01.17.10
Scientists uncovered 13 new genetic mutations that influence the biology at the heart of type 2 diabetes.
Five of the newly discovered variants increase the risk of developing the disease, which affects more than two million people in the UK.
The mutations have an impact on blood glucose regulation, the body's ability to respond to insulin, and the function of insulin-secreting beta cells in the pancreas.
medpagetoday.com | Submitted by shocklime, 12.11.08
Type 1 diabetes and celiac disease, which tend to occur together, share a common genetic background, researchers here said. The finding implies that the two conditions also may share causative biological mechanisms, according to John Todd, Ph.D., of the University of Cambridge, and colleagues.
medpagetoday.com | Submitted by chtine, 11.20.08
BOSTON, Nov. 19 -- Screening for gene variants associated with type 2 diabetes does not add much to conventional risk factors in identifying patients likely to develop the disorder, results of two studies showed.
A genotype score based on single nucleotide polymorphisms at 18 locations previously found to be associated with type 2 diabetes improved prediction in no more than 4% of participants tested, reported James B. Meigs, M.D., M.P.H., of Massachusetts General Hospital, and colleagues in the Nov. 20 issue of the New England Journal of Medicine.
medpagetoday.com | Submitted by Jordanna, 09.25.08
Two common genetic variants appear to contribute to the development of type 2 diabetes for some patients with impaired glucose tolerance, found researchers here. But lifestyle moves seem to be able to combat the enhanced risk.
medpagetoday.com | Submitted by Jordanna, 09.25.08
Several genetic regions appear to contribute to the risk of developing type 2 diabetes, three research groups have found in a major collaborative effort.