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The article states that more MS patients are tend to be born in the spring time. the HLA-DRB1*15 allele is said to have a increase risk of MS and is found more often in people born in the spring. Vitamin D is said to influence HLA-DRB1*15 to being expressed since vitamin D fluctuates between seasons mothers in spring are said to have a higher risk though not proven yet. So in theory the lack of Vitamin D production will impair the thymus to rid rogue t cells which eat away at the myelin sheath of nerve fibers.
For some time, scientists have known that there is a link between being born in the spring and the risk of contracting multiple sclerosis. According to a new study in the journal Neurology, this may have something to do with the HLA-DRB1 gene, and specifically with the HLA-DRB1*15 allele of this gene. The study suggests that a deficit of vitamin D, which influences HLA-DRB1*15, could lead to an increased risk of multiple sclerosis in later life.
For some time, scientists have known that there is a link between being born in the spring and the risk of contracting multiple sclerosis. According to a new study in the journal Neurology, this may have something to do with the HLA-DRB1 gene, and specifically with the HLA-DRB1*15 allele of this gene. The study suggests that a deficit of vitamin D, which influences HLA-DRB1*15, could lead to an increased risk of multiple sclerosis in later life.
FRIDAY, Sept. 11 (HealthDay News) -- Two genes in mice have been linked to improvements in the body's ability to repair itself when afflicted with multiple sclerosis, potentially leading to more effective treatments, a U.S. scientist reports. "Most MS genetic studies have looked at disease susceptibility -- or why some people get MS and others do not," study author Allan Bieber, a Mayo Clinic neuroscientist, said in a Mayo news release. "This study asked, among those who have MS, why do some do well with the disease while others do poorly, and what might be the genetic determinants of this difference in outcome."
Small variations in certain genes were more common in multiple sclerosis patients who showed good responses to beta-interferon, while variations in some other genes were associated with poor response, researchers here said
Although women are more frequently affected with multiple sclerosis, men who have MS are twice as likely to pass it on to their offspring as are women with the disease, according to researchers
New genetic contributors to multiple sclerosis have been uncovered for the first time in 35 years, according to researchers here

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